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Vetoryl (Trilostane)

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Full information about Vetoryl

General Information on Vetoryl

Vetoryl is indicated for the treatment of Cushing’s disease or hyperadrenocorticism in dogs. Usually, this disorder is common in dogs that are older than 6 years of age. The generic name of this drug is Trilostane.

Hyperadrenocorticism is marked by the abnormal production of a hormone called glucocorticoid. This happens either due to adrenocortical tumor or improper functioning of the pituitary glands. Common symptoms associated with this condition are: increased thirst, frequent urination, increased appetite, hair loss, thin skin, brittle hair, depression, lethargy, and abdominal extension.

The active ingredient in this drug, Trilostane, inhibits the activity of the enzyme that causes the excessive production of cortisol. As cortisol level decreases, the symptoms of hyperadrenocorticism begin to heal. However, Vetoryl does not cure hyperadrenocorticism. In fact, as of now, there is no cure for this condition. This basically means that your pet will need to be given Vetoryl for the rest of its life.

Vetoryl is meant for oral administration only. It is available in the form of oral capsules, which come in the following strengths: Vetoryl 10 mg, 30 mg, and 60 mg. As this drug is a prescription drug, you can buy Vetoryl only if you have a vet’s prescription for it.

Side effects of Vetoryl

In some cases, Vetoryl is known to cause serious side effects. In rare cases, this drug may cause death. It is essential that you discuss the risks associated with Vetoryl with your veterinarian before administering it your pet.

You should not give Vetoryl to a pet that is allergic to any of the ingredients used in this drug. Consult your veterinarian if your pet experiences an allergic reaction after being given Vetoryl. Hives, swelling, severe skin rashes, or itching are some of the common side effects noticed during an allergic reaction.

Vetoryl is contraindicated in pets with liver or kidney disease. Do not administer this drug to a pregnant pet. Consult your veterinarian before administering Vetoryl to a lactating pet.

Common side effects associated with Vetoryl may include:

  • Diarrhea
  • Vomitting
  • Lack of energy
  • Weakness
  • Reduced appetite
  • Lethargy

In case any of these side effects become severe or continue to occur for a long time, you must inform your veterinarian.

Consult your veterinarian if your pet experiences any of the following serious side effects:

  • Bloody diarrhea
  • Adrenal necrosis
  • Depression
  • Hypoadrenocortical crisis
  • Collapse
  • Renal failure
  • Muscle tremors
  • Skin reactions

Dosage of Vetoryl

The dosage of Vetoryl depends on the pet’s weight. The recommended dosage range is 1 mg/lb to 3 mg/lb. Vetoryl should be administered once a day. This drug should be administered with food.

Vetoryl is not meant for human use. You should wash your hands before and after administering this drug. Store Vetoryl oral capsules at room temperature between 20°-30°C.


Before you buy Vetoryl, inform your veteriniarian if your pet is on any ACE (angiotensin converting enzyme) inhibitors or potassium sparring diuretics. Serious complications may occur if these drugs are administered in combination with Vetoryl. Consult your veterinarian before administering any new medication to your pet, including over-the-counter drugs and mineral supplements.

Before you buy Vetoryl online, it is recommended that you confirm the authenticity of the provider.

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