Buy Zaroxolyn from Canadian & International Pharmacies
Zaroxolyn (Metolazone)and/or alternatives
Zaroxolyn 2.5mg from $0.45 USD/tabletZaroxolyn 2.5mg
Manufactured by: Aventis Pharma Inc.
Product of Canada. Shipped from CanadaRxPrescription Required
Metolazone 5mg from $0.67 USD/tabletMetolazone 5mg
Generic Alternative to Zaroxolyn
Marketed as Zytanix in India
Manufactured by: Zydus Cadila
Product of India. Shipped from IndiaRxPrescription Required
Basic Information On Zaroxolyn
Zaroxolyn is an oral diuretic used to treat high blood pressure and fluid retention (edema). High blood pressure can cause strokes, kidney problems and heart attacks. The Zaroxolyn drug blocks salt and fluid retention in the kidneys and increases the amount of water and salt removed from the blood by the kidneys. Thus, it decreases water and salt reabsorbed into the blood stream from the kidneys. It increases urine volume and decreases blood volume. This lowers blood pressure and stops excess fluid accumulation in heart failure. It is also called the ‘water pill”. It is chemically related to thiazide class of diuretics and works similarly. It also reduces swelling/fluid retention caused by congestive heart failure or kidney disease like nephrotic syndrome.
Precautions / Side Effects Of Zaroxolyn
Zaroxolyn contains Metolazone. It can cause minor side effects like abdominal bloating and pain, headaches, nausea, vomiting, blurred vision, insomnia, vertigo (a spinning sensation), joint pains and dry mouth. In rare cases, brand or generic Zaroxolyn may cause more severe side effects like dizziness, low blood pressure, high blood sugar, lethargy, irregular heartbeats, gout, muscle cramps, depression, rapid heart rate and yellowing of skin.
Metolazone is excreted by the renal route. Therefore, it should be given carefully to patients with renal impairment as it may cause accumulation. You should avoid alcohol as it may aggravate side effects like hypotension. Your serum electrolyte should be measured at regular intervals to check for fluid or electrolyte imbalance, such as: hypochloremic alkalosis, hyponatremia, and hypokalemia. The risk of hypokalemia increases in case of high dosage, liver diseases, or rapid diuresis. A low salt diet and hot weather may produce a low salt syndrome. Use of brand or generic Zaroxolyn necessitates serum and urine electrolyte measurement particularly if you have protracted vomiting, severe diarrhea, or if you are receiving parenteral fluids.
The recommended Zaroxolyn dosage for treating fluid retention is 5 mg to 20 mg, depending on the severity of the condition. It is usually taken once daily but some patients may not need a daily dose. For treating high blood pressure, 2.5 mg to 5 mg of Zaroxolyn is given daily. The dosage may be changed according to body’s response to the drug or side effects exhibited. Each change in dosage takes many weeks to show its therapeutic efficacy. The dosage basically depends on the disease being treated, other drugs taken by the patient and body’s response to this medicine. The medicine is taken orally, with or without food.
Buy Zaroxolyn From North Drug Store
North Drug Store supplies brand or generic Zaroxolyn as 2.5 mg and 5 mg tablets. You can buy Zaroxolyn from North Drug Store as it offers ease of ordering and low price guarantee.
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IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.