Buy Fosamax Plus D from Canadian & International Pharmacies
Fosamax Plus D (Alendronate Sodium/Vitamin D)and/or alternatives
Fosamax Plus D 70mg/2800IU from $4.33 USD/tabletFosamax Plus D 70mg/2800IU
Marketed as Fosavance in Turkey
Manufactured by: Merck Sharp & Dohme
Product of Turkey. Shipped from TurkeyRxPrescription Required
Fosamax Plus D 70mg/5600IU from $8.92 USD/tabletFosamax Plus D 70mg/5600IU
Marketed as Fosamax Plus 70mg/140mcg in New Zealand
Manufactured by: Merck
Product of New Zealand. Shipped from New ZealandRxPrescription Required
Fosamax Plus D 70mg/5600IU is currently unavailable from Canada
Alendronate Sodium/Vitamin D 70mg/5600IU from $6.33 USD/tabletAlendronate Sodium/Vitamin D 70mg/5600IU
Generic Alternative to Fosamax Plus D
Marketed as Apo-Alendronate/Vitamin D in Canada
Manufactured by: Apotex Corporation
Product of Canada. Shipped from CanadaRxPrescription Required
General Information on Fosamax Plus D
Fosamax Plus D is used for treating certain types of osteoporosis and increasing bone mass. Your bones may become thinner and brittle as you age, especially if you take corticosteroids for a long period or are experiencing menopause.
Fosamax Plus D is a combination of two drugs, Cholecalciferol and Alendronate. Cholecalciferol is a Vitamin D3 supplement and Alendronate is a bisphosphonate. Cholecalciferol helps the body absorb calcium and is needed for the maintenance of healthy bones, while Alendronate slows down bone loss.
Fosamax Plus D is available in the form of oral tablets.
Side effects of Fosamax Plus D
Before you buy Fosamax Plus D, inform your doctor if you have a disorder of the esophagus (e.g. achalasia or esophageal stricture), trouble swallowing, an intestinal or stomach disorder (e.g. ulcer), low calcium levels, or if you have any trouble sitting upright or standing for 30 minutes.
In some cases, bisphosphonates may lead to serious jawbone problems in patients (termed as osteonecrosis), especially if they have poor dental hygiene, have undergone a dental surgery or tooth removal, wear ill-fitting dentures, or are suffering from cancer, gum disease or infection, or anemia. As such, inform your doctor immediately if you experience jaw pain.
Constipation, stomach pain, nausea, diarrhea, or gas may commonly surface as side effects of Fosamax Plus D. Inform your doctor immediately if any of these symptoms become too troublesome.
Some serious side effects associated with Fosamax Plus D include muscle, joint or bone pain, jaw pain, swelling of the ankles, feet, hands or joints, black or tarry stools, or dark colored vomit.
In rare cases, Fosamax Plus D may lead to serious irritation or ulcers in the esophagus. Notify your doctor at once if you experience worsening or new heartburn, difficulty or pain while swallowing, or chest pain.
Some patients may develop an allergic reaction to Fosamax Plus D. Discontinue using the drug if you experience severe dizziness, facial swelling, hives, or difficulty breathing after taking Fosamax Plus D. Seek immediate medical attention if these symptoms persist even after discontinuing the drug.
Dosage of Fosamax Plus D
Usually, your doctor will recommend you to take one Fosamax Plus D 70mg Alendronate/2800IU vitamin D3 tablet once a week. In some cases, he or she may advise you to take one Fosamax Plus D 70mg Alendronate/5600IU vitamin D3 tablet per week. The dosage depends on your medical condition and response to treatment.
Take the tablet first thing in the morning on an empty stomach. Do not eat or drink anything for 30 minutes after taking a dose.
Swallow the tablet whole. Do not crush, chew, break or dissolve it. Take Fosamax Plus D with plain water (not mineral water). Do not bend over, recline, or lie down for at least half an hour after taking the tablet.
Drug Interactions of Fosamax Plus D
Do not buy Fosamax Plus D and use it along with supplements, antacids, or drugs that contain calcium, aluminum, magnesium, or any other mineral, as they may affect the way Fosamax Plus D is absorbed by your body. If taking these is inevitable, maintain a gap of at least 30 minutes before taking Fosamax Plus D.
Also do not take Fosamax Plus D along with NSAIDs such as celecoxib, diclofenac or meloxicam, as they may interact with one other.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.