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Inhibace Plus (Cilazapril/Hydrochlorothiazide)

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Full information about Inhibace Plus

General Information on Inhibace Plus

Inhibace Plus is indicated for the treatment of mild to moderate hypertension, or high blood pressure. This drug is a combination of two medicines, Cilazapril and Hydrochlorothiazide.

Both, Cilazapril and Hydrochlorothiazide, help in controlling blood pressure. Cilazapril, an ACE inhibitor, relaxes blood vessels and allows the heart to work more efficiently. Hydrochlorothiazide is a thiazide diuretic and helps in controlling blood pressure by removing excess water and salt. Inhibace Plus is prescribed to hypertension patients who are already taking Cilazapril and Hydrochlorothiazide separately.

Inhibace Plus is meant for oral administration only. You can buy Inhibace Plus in form of oral tablets. It is available in only one strength, Inhibace Plus 5mg/12.5mg per tablet. That is, each tablet of Inhibace Plus contain 5mg of Cilazapril and 12.5mg of Hydrochlorothiazide.

In addition to the two active ingredients, Cilazapril and Hydrochlorothiazide, Inhibace oral tablets also contain the following inert ingredients: Lactose monohydrate, hypromellose, maize starch, sodium stearyl fumarate, purified talc, red iron oxide, and titanium dioxide.

Side effects of Inhibace Plus

Inhibace Plus is contraindicated in patients who cannot pass urine or have a known hypersensitivity to:

  • Cilazapril, Hydrochlorothiazide, or any other ingredient present in Inhibace Plus
  • Other ACE inhibitors such as quinapril, fosinopril, ramipril, and others
  • Sulfonamide drugs such as sulfamethoxazole

Before using this anti-hypertension drug, you should:

  • Inform your doctor about your medical history, especially if you have/have had a serious liver or kidney disease.
  • Discuss the potential risks of using Inhibace Plus with your doctor

Common and less serious side effects of Inhibace Plus may include, but are not restricted, to the following:

  • Nausea
  • Increased urination
  • Dizziness
  • Headache
  • Drowsiness
  • Cough
  • Cold-like symptoms
  • Unusual tiredness

You should consult your doctor if you experience any of the aforementioned side effects and it causes concern.

Serious side effects of Inhibace Plus may include, but are not restricted, to the following:

  • Chest Pain
  • Abdominal swelling
  • Muscle cramps or pain
  • Tingling or numbness in feet or hands
  • Signs of a liver problem like nausea, vomitting, abdominal pain, loss of appetite, yellow eyes or skin
  • Signs of hypotension (also called low blood pressure) like fainting, lightheadedness, or dizziness

You should consult your doctor immediately if you experience any of the side effects listed above.

Certain drugs should be avoided during pregnancy and while breastfeeding. The safety of Inhibace Plus in pregnant and lactating women has not been established. If you are pregnant or breastfeeding a baby, consult your doctor before using Inhibace Plus.

Dosage of Inhibace Plus

The recommended dosage is one tablet of Inhibace Plus each day. However, the actual dosage varies from patient to patient. Your doctor will prescribe you the correct dosage after studying the severity of your condition, your medical history, your kidney and liver function, and your response to the treatment.


Certain drugs may interact with Inhibace Plus. This is why it is necessary that, before you buy Inhibace Plus, you inform your doctor about all the other drugs you are taking. Names of some drugs that are may interact with Inhibace Plus are as follows:

  • Lithium
  • Diuretics
  • Barbiturates
  • Anti-diabetes drugs
  • Narcotic medications
  • Rituximab
  • Cyclosporine
  • Corticosteroids
  • Drugs that increase blood potassium levels
  • Norepinephrine

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