Buy Inhibace Plus from Canadian & International Pharmacies
Inhibace Plus (Cilazapril/Hydrochlorothiazide)and/or alternatives
Inhibace Plus 5/12.5mg from $1.57 USD/tabletInhibace Plus 5/12.5mg
Manufactured by: Hoffmann-LaRoche Ltd.
Product of Canada. Shipped from CanadaRxPrescription Required
Cilazapril/Hydrochlorothiazide 5/12.5mg from $0.58 USD/tabletCilazapril/Hydrochlorothiazide 5/12.5mg
Generic Alternative to Inhibace Plus
Marketed as Apo-Cilazapril/HCTZ in Canada
Manufactured by: Apotex Corporation
Product of Canada. Shipped from CanadaRxPrescription Required
General Information on Inhibace Plus
Inhibace Plus is indicated for the treatment of mild to moderate hypertension, or high blood pressure. This drug is a combination of two medicines, Cilazapril and Hydrochlorothiazide.
Both, Cilazapril and Hydrochlorothiazide, help in controlling blood pressure. Cilazapril, an ACE inhibitor, relaxes blood vessels and allows the heart to work more efficiently. Hydrochlorothiazide is a thiazide diuretic and helps in controlling blood pressure by removing excess water and salt. Inhibace Plus is prescribed to hypertension patients who are already taking Cilazapril and Hydrochlorothiazide separately.
Inhibace Plus is meant for oral administration only. You can buy Inhibace Plus in form of oral tablets. It is available in only one strength, Inhibace Plus 5mg/12.5mg per tablet. That is, each tablet of Inhibace Plus contain 5mg of Cilazapril and 12.5mg of Hydrochlorothiazide.
In addition to the two active ingredients, Cilazapril and Hydrochlorothiazide, Inhibace oral tablets also contain the following inert ingredients: Lactose monohydrate, hypromellose, maize starch, sodium stearyl fumarate, purified talc, red iron oxide, and titanium dioxide.
Side effects of Inhibace Plus
Inhibace Plus is contraindicated in patients who cannot pass urine or have a known hypersensitivity to:
- Cilazapril, Hydrochlorothiazide, or any other ingredient present in Inhibace Plus
- Other ACE inhibitors such as quinapril, fosinopril, ramipril, and others
- Sulfonamide drugs such as sulfamethoxazole
Before using this anti-hypertension drug, you should:
- Inform your doctor about your medical history, especially if you have/have had a serious liver or kidney disease.
- Discuss the potential risks of using Inhibace Plus with your doctor
Common and less serious side effects of Inhibace Plus may include, but are not restricted, to the following:
- Increased urination
- Cold-like symptoms
- Unusual tiredness
You should consult your doctor if you experience any of the aforementioned side effects and it causes concern.
Serious side effects of Inhibace Plus may include, but are not restricted, to the following:
- Chest Pain
- Abdominal swelling
- Muscle cramps or pain
- Tingling or numbness in feet or hands
- Signs of a liver problem like nausea, vomitting, abdominal pain, loss of appetite, yellow eyes or skin
- Signs of hypotension (also called low blood pressure) like fainting, lightheadedness, or dizziness
You should consult your doctor immediately if you experience any of the side effects listed above.
Certain drugs should be avoided during pregnancy and while breastfeeding. The safety of Inhibace Plus in pregnant and lactating women has not been established. If you are pregnant or breastfeeding a baby, consult your doctor before using Inhibace Plus.
Dosage of Inhibace Plus
The recommended dosage is one tablet of Inhibace Plus each day. However, the actual dosage varies from patient to patient. Your doctor will prescribe you the correct dosage after studying the severity of your condition, your medical history, your kidney and liver function, and your response to the treatment.
Certain drugs may interact with Inhibace Plus. This is why it is necessary that, before you buy Inhibace Plus, you inform your doctor about all the other drugs you are taking. Names of some drugs that are may interact with Inhibace Plus are as follows:
- Anti-diabetes drugs
- Narcotic medications
- Drugs that increase blood potassium levels
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.