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Mesasal (Mesalamine)

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Full information about Mesasal

General Information on Mesasal

Mesasal is indicated for the treatment of acute inflammatory bowel diseases such as ulcerative colitis and Crohn’s colitis. The drug is specifically used to manage and prevent relapse of ulcerative colitis.

Mesalamine (5-aminosalicylic acid), the main active ingredient in the medication, belongs to a group of medicines known as salicylates. It works to reduce inflammation in the large intestine and also controls other symptoms.

Mesasal is available in the form of a tablet and a suppository. The tablet is available in two strengths- Mesasal 250mg and Mesasal 500mg. You may buy Mesasal online, but you must consult your doctor before using it in any form as it is a prescription only drug and may also cause health complications.

Side effects of Mesasal

You should not buy Mesasal if you are hypersensitive to any ingredient in it. It may not be the right medication for people with specific medical problems. Before starting the treatment, tell your doctor about your medical problems such as heart problems, reduced kidney function/liver function, or pyloric stenosis.

Mesasal may cause mild to severe side effects in some people. Mild headache, dizziness, acne, stomach cramps, indigestion, loss of hair, nausea, loss of appetite, gas, back/joint pain, diarrhea, heartburn, or vomiting are some less serious side effects associated with the medication. These side effects wane with time as your body gets used to the drug and can also be treated by your doctor. If any side effects become bothersome or persist, consult your doctor.

Some people may also experience severe side effects after taking a dose of Mesasal. Severe headaches, mood swings, anxiety, fast heartbeat, pale or blue skin, swelling of the stomach, unusual weakness/tiredness, itching or skin rashes are some severe side effects associated with the drug. This is not a complete list of severe side effects. Stop using Mesasal and seek medical attention immediately if you notice any severe side effects after using the drug.

Mesasal should not be used for pediatric patients. Elderly patients have reduced kidney function, so regular monitoring of kidney function is necessary if the drug is prescribed to geriatric patients. Pregnant women and nursing mothers should buy Mesasal only after learning about the risks and benefits of using the drug from their doctor.

Dosage of Mesasal

Your doctor will provide specific instructions regarding the dosage. The dosage depends on the form of medication prescribed in the treatment. The recommended Mesasal dose to treat Crohn’s disease and acute ulcerative colitis is two Mesasal 250mg tablets three times daily. The recommended dose to maintain and prevent relapse of acute ulcerative colitis is one Mesasal 250mg tablet three times daily.

Your doctor may recommend a different dose other than the ones mentioned above. Take the medication 30 minutes prior to eating your meal. Swallow the tablet whole, and do not crush or chew it.


Mesasal may potentially interact with other medicines you are using and cause side effects. It may interact with drugs such as Furosemide, Digoxine, Spironolactone, Azathioprine, Sulfinpyrazone, Probenecid, Warfarin, Lactulose, NSAIDs, Thioguanine, Methotrexate, or 6-Mercaptopurine.

Before you buy Mesasal, inform your doctor about every medicine you are using, which includes prescription drugs, over the counter medications, and herbal supplements.

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