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Pentasa (Mesalamine ER)

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Full information about Pentasa

Basic Information On Pentasa

Pentasa is an anti-inflammatory drug which is sold as controlled-release capsule, meant for oral route of administration. The drug is used for the treatment of ulcerative colitis which is mild to moderate in severity. Thus it is used to cure the inflammations of the digestive-tract. It is also used for remission induction. It is an amino-salicylate drug which particularly has its action on the gut and bowels. Therefore, the drug has certain systemic side-effects also. The drug is also indicated for Crohn’s disease which is mild to moderate in severity. The salicylic acid component of brand or generic Pentasa is an anti-oxidant. The drug acts by inhibiting the production of prostaglandin and blocking cyclo-oxygenase in the colon which results in diminishing the inflammation.

Precautions / Side Effects Of Pentasa

The common and expected side effects of Pentasa include flatulence, nausea, diarrhea and cramps. You may experience uncommon side effects with the drug which may include exacerbation of colitis, intestinal nephritis, hair loss, bleeding, bruising, sore throat, fever, malaise and headache. Uncommon side effects of Mesalamine/5-Aminosalicyclic Acid also include hypersensitivity reactions such as uritcaria, hives and rashes. If you experience the above mentioned uncommon side effects or the common side effects worsen, then consult your physician.

Rare side effects of Pentasa drug include blood disorders such as leucopenia, agranulocytosis, aplastic anemia, thrombocytopenia and neutropenia. Other rare side effects include hepatitis, acute pancreatitis and nephrotic syndrome. The mesalamine component of Pentasa has additional side effects (which are rare) such as allergic myocarditis, allergic lung reactions and methaemoglobinaemia. As mentioned above Mesalamine/5-Aminosalicyclic Acid has its side effects on the liver, kidney and blood. Patients with hepatic or renal impairment or blood disorders should administer the drug with caution and with physician’s advice.

Pentasa Dosage

Ulcerative colitis that is mild to moderate in severity is treated symptomatically. The recommended dose of Pentasa in the treatment of active ulcerative colitis and induction of remission is 1 g to be administered four times a day, which is a total dose of 4 g per day. This means either 2 Pentasa of 500 mg capsules or 4 Pentasa of 250 mg capsules each day. The recommended duration of the treatment is up to a period of 8 weeks. Also, it is recommended that blood tests should be done before and after the treatment with the brand or generic Pentasa.

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Buy Pentasa from our recognized mail order pharmacy at doses of 250 mg and 500 mg in varied quantities and be assured of our quick service.

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