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Prometrium (Progesterone Micronized)

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Full information about Prometrium

Basic Information On Prometrium

Prometrium is a synthetic version/form of the female sex hormones that occurs naturally, called progesterone. It is a progestin. It is a steroid hormone that is responsible for maintaining gestation (pregnancy), embryogenesis and female menstrual cycle. The drug is also used for the treatment of secondary amenorrhea. The drug maintains high levels of progesterone (synthetic) in the body; it thus fools the body and makes it think that ovulation has occurred. This helps in preventing the release of the eggs from the ovary. In post-menopausal women, who administer estrogen tablets, the drug is used to prevent the endometrial hyperplasia. Brand or generic Prometrium acts primarily on the female reproductive-tract, hypothalamus, pituitary and mammary glands. It acts by reducing release and frequency of release of the GnRH (gonadotropin releasing hormone).

Precautions / Side Effects For Prometrium

The common side effects of Prometrium are thirst, stomach spasms, abdominal pain, cramps, athralgia, nocturia, lightheadedness, drowsiness, headache, nervousness, insomnia, depression, aggression, emotional instability, mood swings, sleep disorder, forgetfulness, gastralgia, dopiness, pyrosis, soreness of breasts, enlargement of breast, swelling, muscular pain, joint pain, queasiness, holding of fluid, bad temper, xerostomia, nausea, vomiting, constipation, flatulence, hot flushes, loose bowels, diarrhea, decreased libido, increased urination during the night, increased appetite and fatigue. If any of the above mentioned side effects prolong or worsen with Progesterone Micronized, then contact your health care provider.

Serious side effects of Prometrium drug include migraine (chronic vascular headache), alterations of vision or loss of vision, jaundice like symptoms (skin color turning yellow), bile-stones, acute pain in the stomach, bloated stomach or soreness of stomach, severe vomiting, seizures, trembling, puffing-up of fingers, ankles and/or calf, insensitivity of an arm or leg, chest beating, weakness in the body, swelling and pain in the breasts, spitting blood, breathlessness, popping eyes, and abnormal vaginal bleeding. Progesterone Micronized also shows psychological effects such as anxiety, dejection etc.

Prometrium Dosage

In the treatment to prevent endometrial hyperplasia, the recommended dose of Prometrium is 200 mg in post-menopausal women who are taking estrogen tables. The drug is administered as a single dose, preferably at bed time, on a daily basis. It is administered orally in form of capsules for 12 days in a row, every 28-day cycle. In the treatment of secondary amenorrhea 400 mg of Brand or generic Prometrium is administered in capsule form. The drug is administered at bed time (preferably) and for a period of 10 days. The capsule is administered with water in a standing position.

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