Buy Rifamate from Canadian & International Pharmacies
Rifamate (Isoniazid/Rifampacin)and/or alternatives
Rifamate 150/300mg from $1.36 USD/tabletRifamate 150/300mg
Marketed as Rifinah in European Union
Manufactured by: Movianto
Product of United Kingdom. Shipped from United KingdomRxPrescription Required
General Information on Rifamate
Rifamate is an antibiotic. It prevents bacteria from spreading in your body. Its generic name is Isoniazid and Rifampin. It is used to treat and prevent Tuberculosis bacteria from multiplying in the body. It treats only the bacteria and not the infection itself. It is not to be taken for treating the common cold or flu.
Rifamate prevents tuberculosis causing bacteria to spread in the body. However, it will not treat a bacteria caused infection. It will only kill the bacteria that are causing infection. Rifamate is administered as capsules, syrup and intravenous infusion. It comes in two strengths; Rifamate 300mg and Rifamate 150 mg.
Rifamate reduces the effectiveness of birth control pills. Before you buy Rifamate, inform your doctor about your allergies or liver disease, if you have.
Side effects of Rifamate
Some major side effects of Rifamate are given below.You must contact your doctor immediately if you witness these side effects before it leads to serious problems.
- Any allergic reaction
- Fever, chills, body ache, flu symptoms
- Joint pain, swelling
- Easy bruising/bleeding, weakness
- nausea, stomach pain, loss of appetite
- clay colored stool, jaundice
- Blurred vision
- abnormal behavior
Do not wear contact lenses during the treatment. Isoniazid and Rifampin can turn your urine, stool, sweat, tear, saliva and even contact lenses to turn red or orange in color. This medicine can harm the unborn baby. Before you buy Rifamate, make sure your doctor knows about all your allergies and medical history, and if you are pregnant.
Dosage of Rifamate
In general, treatment should be continued until bacterial conversion and maximal improvement have occurred. Adults should take 2 Rifamate capsules once a day not exceeding 600mg/day.
Take the medication as prescribed by the doctor. The Rifamate capsule must be taken with water, empty stomach, 1 or 2 hours before or after meals. It must be taken for the full prescribed time even if your symptoms seem to have improved before you completed the medicine schedule.
If you miss a dose and it is almost time for the next dose, then skip it and continue with the normal routine. Do not take 2 doses together. Over dosing could lead to severe side effects like nausea, abdominal pain, tiredness etc. You might also be required to supplemental Vitamin B6 daily during treatment. This stops the numbness caused by low levels of the vitamin.
A total of 677 drugs, and 11 diseases are known to interact with Rifamate, of which 49 drug interactions are major, 564 are moderate and 64 are minor. Some of the major drug interactions are given below:
Alcohol increases the risk of liver damage during this medication. Food rich in Histamine such as fish or cheese may cause a flushing reaction in some of the patients.The diseases interacting with Rifamate are:
- Hematopoietic Disturbances
- Liver Disease
- Enzyme Induction
- Peripheral Neuropathy
- Renal Dysfunction
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.