Buy Rifater from Canadian & International Pharmacies
Rifater (Isoniazid/Rifampin/Pyrazinamide)and/or alternatives
Rifater 50/120/300mg from $0.75 USD/tabletRifater 50/120/300mg
Manufactured by: Sanofi Aventis
Product of United KingdomRxPrescription RequiredCurrently Unavailable
General Information on Rifater
Rifater is an antibiotic. It prevents bacteria from spreading in your body. It is a combination of 3 drugs- Isoniazid, Pyrazinamide and Rifampin. All 3 of them are antibiotics used to treat and prevent Tuberculosis causing bacteria from multiplying in the body. The combination of Isoniazid, Pyrazinamide and Rifampin is used to treat Tuberculosis.
Rifampin works by killing the bacteria that are causing infection. Isoniazid prevents the bacteria from making mycolic acid which is needed to form the cell walls of the bacteria. It also disrupts the metabolism of the bacteria, forcing it to die.
Rifater is administered as tablets. It comes in 3 strengths- Rifater 50mg, Rifater 120 mg and Rifater 300 mg.
Side effects of Rifater
Some of the major side effects caused by Rifater are given below:
- Any allergic reaction
- Fever, body ache, chills, symptoms of flu
- Swelling in joints and pain
- Coughing up blood
- Dark or Bloody stools, jaundice
- Bloody or dark urine, change in the amount of urine produced
- Changes in vision
- Memory problems
The less severe side effects are given below:
- Dizziness, drowsiness, nausea
- Gas, mild stomach upset or cramps
- Headache, heartburn
- Mild joint or muscle aches
- Red or orange colored urine, stool, tears, sweat or saliva
You must avoid wearing contact lenses during the treatment. The most common side effect of Isoniazid is that it affects the nervous system and liver. Pyrazinamide cause Hepatic reaction as most common side effect. This medicine can have harmful effect on the fetus. Before you buy Rifater, make sure you consult your doctor about allergies to any ingredient present in the medicine and your medical history. You should also seek advice in case you are pregnant. Nursing should be avoided as the active ingredients of Rifater enter the mammary glands as well.
Dosage of Rifater
In general, treatment should be continued until bacterial conversion and maximal improvement have occurred. Patients should be given the medication in the following way 1 or 2 hours after the meals with a glass full of water.
- Patients weighing less than 44 kg - 4 tablets
- Patients weighing between 45-54 kg - 5 tablets
- Patients weighing more than 55 kg - 6 tablets
The ratio of Rifater is not appropriate for patients under 15 years of age. Take the medication as prescribed by the doctor. Usually it should be followed for 2 months of time.
Total of 676 drugs, 2 Alcohol/Foods and 17 diseases are known to interact with Rifater. Some of the major drug interactions are given below:
Alcohol interacts with the active ingredients of Rifater, thus increasing the risk of liver damage during the treatment. Histamine rich food such as fish (Tuna) or cheese may cause a flushing reaction in some of the patients. Some of the diseases interacting with Rifater are:
- Hematopoietic Disturbances
- Liver Disease
- Enzyme Induction
- Peripheral Neuropathy
- Renal Dysfunction
- Diabetes Mellitus
Contact your Doctor before you buy Rifater, in case of any allergies and past medical history. Blood tests should be done to check the liver functioning before starting the treatment.
* All trademarks and registered trademarks are the property of their respective owners.
IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.