Buy Duodopa from Canadian & International Pharmacies
Duodopa (Levodopa/Carbidopa)and/or alternatives
Duodopa 2000/500mg from $1,375.00 USD/packDuodopa 2000/500mg
Manufactured by: Solvay Pharmaceuticals
Product of United Kingdom. Shipped from United KingdomRxPrescription Required
General Information on Duodopa
Duodopa is indicated for the management of severe involuntary movements associated with Parkinson’s disease. The generic name of this drug is Levodopa/Carbidopa Intestinal Gel. Duodopa falls under a category of drugs referred to as anti-Parkinson medicines.
Duodopa works by improving the levels of certain chemicals that help the patient regain control over his/her movements as well as posture. Duodopa contains two active ingredients, levodopa and carbidopa. In addition, it also contains the following inactive ingredients: purified water and carmellose sodium.
Side effects of Duodopa
Before starting treatment, discuss all the possible risks attached with this anti-Parkinson drug with your doctor. The side effects of Duodopa are divided in two categories, less severe and severe.
Less severe side effects of Duodopa may include, but are not restricted to: abnormal involuntary muscle movements, loss of appetite, vomiting, nausea, abnormal dreams, dark saliva, dizziness, lightheadedness, slow movements, increased sex drive, drowsiness, or skin pigmentation.
Severe side effects of Duodopa may include, but are not restricted to: painful or difficult urination, blood in the urine, depression, anemia symptoms (shortness of breath, tiredness, or pale appearance) forgetfulness, fainting, numbness in the feet or hands, easy bruising, easy or unusual bleeding, or mild skin rash.
Patients who have a known hypersensitivity to levodopa and/or carbidopa should not buy Duodopa. A hypersensitive reaction, if left untreated, can sometimes prove dangerous. Symptoms associated with a hypersensitive reaction include the following: hives, skin rash, facial flushing, itching, swelling of the upper face, or difficulty breathing or swallowing.
Duodopa is contraindicated in patients who have/have had any of the following medical conditions: severe heart failure, severe liver insufficiency, narrow-angle glaucoma, hormonal problems, melanoma, acute stroke, or severe cardiac arrhythmia.
To make sure Duodopa is completely safe for you, inform your physician about your medical history, especially if you have or ever had any of the following: serious lung problems, heart attack, asthmatic bronchitis, gastric ulcer, hormonal disturbances, mental disorders such as depression, or seizures.
You should not use Duodopa if you have taken a MAO inhibitor. Examples of this drug type include such as Selegiline, Phenelzine, Isocarboxazid, or Tranylcypromine in the last 14 days.
The safety and efficacy of Duodopa in pregnant and lactating women has not been studied. If you are pregnant or if you are in the breastfeeding stage, you should use Duodopa only if your doctor recommends it.
Dosage of Duodopa
Duodopa intestinal gel is available in Duodopa 20mg/ml + 5mg/ml strength. This means 1ml of Duodopa intestinal gel contains 20mg of levodopa and 5mg of carbidopa monohydrate.
The daily dose of Duodopa is divided into 3 individually adjusted dosages- a morning dose, a maintenance dose, and an extra dose. Depending on your condition and tolerance to treatment, your doctor will inform you about how much Duodopa you should take in these 3 dosages. It is critical that you take your medication exactly as prescribed by your doctor.
Certain drugs such as antidepressants, antipsychotics, iron supplements, phenytoin, high blood pressure or heart medications, and others may interact with Duodopa. Before you buy Duodopa, inform your doctor about all the drugs you are currently taking.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.