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Safyral (Drospirenone/Ethinyl Estradiol/Levomefolate Calcium)

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Full information about Safyral

General Information on Safyral

Safyral or Beyaz is used as contraceptive to prevent a pregnancy. It is also used to raise foliate levels in women who use a birth control pill. The generic name of this drug is Drospirenone, Levomefolate and Ethinyl estradiol.

Safyral prevents ovulation and alters cervical and uterine lining, thus it gets harder for the sperm to fertilize an egg, or for a fertilized egg to attach itself to the uterus. It also contains Levomefolate, a form of vitamin B that prevents birth defects if pregnancy occurs.

This medication is available in Safyral 0.03mg, Safyral 0.451, and Safyral 0.3 mg strengths. You can buy Safyral online only if you have a doctor’s prescription.

Side effects of Safyral

You should not buy Safyral if you:

  • Have coronary heart, kidney or liver disease
  • Have an adrenal gland disorder
  • Have unusual vaginal bleeding
  • Have uterine or breast cancer
  • Are over 35 years of age

Before you buy Safyral, inform your doctor if you have any of the following:

  • High blood pressure and cholesterol
  • High potassium levels in the blood
  • Gallbladder disease
  • Diabetes
  • Seizures

Some of the mild side effects of this drug are:

  • Headache, nausea, stomach pain
  • Breast pain
  • Weight gain
  • Loss of interest in sex
  • Change in menstrual period

You should consult your doctor immediately if your experience any of the following serious side effects:

  • Sudden weakness
  • Chest pain, sweating and nausea
  • Jaundice
  • Depression

Pregnant women and breastfeeding mothers should avoid Safyral.

Dosage of Safyral

You should take Safyral on the first day of your period or on the first Sunday after your period begins. You should also use back-up birth controls for the first 7 days of using Safyral.

The 28-day birth control pack of Safyral contains reminder pills. One Safyral pill is to be taken with every evening meal or at bedtime. The gap should not exceed 24 hours. Breakthrough bleeding may occur during treatment; if this continues or is very heavy, seek immediate medical help.

Two pills can be taken at once if you forget to take one for a day. If two active pills in the first or second week are missed, take two pills for two days in a row or two pills a day, and one pill a day for the rest of the pack. Use a backup birth control measure at least for one week.

If two active pills in a row are missed in week 3, or if three pills in a row are missed in any of the first 3 weeks, start a new pack on the same day if you are a day one (of your period) starter.

If two or more pills are missed, you may not have a period during the month. If a period is missed for two months in a row, you need to consult your doctor. If you miss one pill in week four, skip that dose and take the next one as directed. In case of an overdose, seek immediate medical help.


The drugs that can hamper the effectiveness of Safyral are bosentan, folic acid, heparin, HIV mediations, antifungal medicines, antibiotics like rifampin, griseofulvin, NSAIDs and seizure medications.

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