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Vesanoid (Tretinoin)

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Full information about Vesanoid

Basic Information On Vesanoid

Vesanoid is involved in the induction of maturation of the acute promyelocytic leukemia cells (APL). It is responsible for the expression of the genes during the development of the embryo. It is also responsible in the normal growth of cells. It is a retinoic acid which is derived from vitamin A (maternal). However, if it is in excess then it can be cancerous (teratogenic). It is available as soft gelatin capsules which is used in the treatment of APL. It is also available in form of gel or cream which is used in the treatment of keratosis pilaris and acne vulgaris. Promyelocytic leukemia gene-retionic acid receptor (PML-RAR) blocks the differentiation of myeloid cells into mature cells, thus causing leukemia. Brand or generic Vesanoid acts by lifting this block and allowing the immature cells (promyelocytes) to differentiate and mature into normal cells.

Precautions / Side Effects For Vesanoid

When Vesanoid drug is used in the treatment of leukemia the side effects experienced are fever, dyspnea, weight gain, peripheral edema and retinoic acid syndrome. If you are using the drug for dermatological treatment then the side effects of Tretinoine may include increase in the sensitivity of the skin and dryness of the affected skin. Sensitive patients may experience reddening, burning, scaling and itching of the skin. In some patients the skin may also become thin. Such patients must avoid removal of the hair using waxing or threading techniques.

In general the common side effects of Vesanoid include dry skin, dry mouth, bone pain, hair loss, increased sweating, nausea, vomiting, itching, rashes, weakness and tiredness. Serious side effects of the drug include dizziness, heart attack, breathlessness, loss of hearing, severe headache, unusual bleeding, unusual bruising and changes in the vision. Serious side effects of Tretinoine also include allergic reactions which may be severe such as itching, difficulty in breathing, hives, tightness of chest and swelling in the face, lips, tongue and mouth. If these side effects occur, then consult your physician.

Vesanoid Dosage

The general recommended dose of Vesanoid is 45 mg/m2/day. The drug is administered as 2 divided even doses. The drug should be administered till remission is complete and is documented. Once the remission is complete the drug should be discontinued after 30 days or after 90-days of therapy. Patients with APL must receive standard chemotherapy regimen after the therapy with brand or generic Vesanoid is induced, unless it is contraindicated. In the dermatological treatment the drug is used as a lotion, gel or cream. The drug is administered by topical application of the drug to the affected part of the skin.

Buy Vesanoid From North Drug Store

Buy Vesanoid at a fixed dose of 10 mg from North Drug Store and be assured of a safe transaction.

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